ABSTRACT
To present the epidemiologic profile and magnitude of ocular malignant tumors [MT] representative of the Saudi population from the Tumor Registry [TR] at King Khaled Eye Specialist Hospital [KKESH]. This study evaluated the demographic information, clinical features including tumor laterality, ocular tissue of origin, and diagnosis of patients from the TR registry between 1983 and 2012 at KKESH, Riyadh, Kingdom of Saudi Arabia. The incidence of MT among Saudi adults [>/= 15 years old], and children [<15 years old] was estimated. The TR recorded 4,146 neoplasms [2,509 [60.5%] benign tumors, and 1,637 [39.5%] MT]. The incidence of MT in children was 3.6 per million/year [M/Y], and 2.4/M/Y for adults. Retinoblastoma [Rb] [n=763, 91%] was the most common ocular malignancy in children. In adults, the most common MT was squamous cell carcinoma [SCC] [n=363, 45.8%], basal cell carcinoma [BCC] [n=186, 23%], uvealmelanoma [n=94, 11.9%], sebaceous gland carcinoma [n=54, 6.8%], lymphomas [orbital, adnexal] [n=46, 5.8%], and others [n=53, 6.8%]. The Rb [7.7/M/Y in <5 years old Saudi children] was less frequent than that reported in some Gulf countries, but higher than that reported from the West. The SCC was less frequent in countries with comparable sun exposure than in other continents, but the incidence remained unchanged over 3 decades. There was a significant increase in BCC between 1983-1992 and 2003-2012. The rates of all cancers remained stable over 3 decades except BCC, which showed a significant rise
ABSTRACT
Late graft failure due to the development of corneal guttata is rare. We report a case of a 58 year old patient who underwent penetrating keratoplasty [PKP] for corneal edema in the right eye. Later, he had phacoemulsification and posterior chamber intraocular lens implantation in the same eye. This was followed by graft decompensation for which a second PKP was performed. The histopathology revealed corneal guttata typical of what is seen in Fuchs' endothelial dystrophy. These findings are discussed with a review of the related literature
ABSTRACT
To report a case of nodular episcleritis at the limbus associated with corenal deposits in a young patient. Observational case report. A 16-year-old Saudi girl developed a pinkish-white, soft, well-demarcated mass, 6 x 5 mm in size and 1mm in height, in the superonasal limal area of the right eye. It was associated with yellowish deposits in the adjacent cornea. histopathological evaluation of the excised lesion revealed chronic inflammation in the deep layer of the episclera with infiltration by lymphocytes and epithelioid cells, in addition to capillary proliferation. subsequently, the patient didn't develop any systemic manifistation or recurrence during the one-year follow-up period. Although nodular episcleritis tends to occure in an older age group, it can also present in young patients. Surgical excision can result in an excellent clinical outcome